Sperm protein 17 is expressed in the sperm fibrous sheath
نویسندگان
چکیده
منابع مشابه
Sperm protein 17 is not expressed on normal leukocytes.
corticosteroids and/or chemotherapy, has so far shown efficacy in only a few cases of cold agglutinin disease.6-11 Asingle course of rituximab also has been used in combination with corticosteroids for the treatment of one case of idiopathic warm hemolytic anemia, leading only to a partial improvement of the hemoglobin level and hemolytic signs.12 Although further studies are warranted on large...
متن کاملCABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheath
BACKGROUND CABYR is a polymorphic calcium-binding protein of the sperm fibrous sheath (FS) which gene contains two coding regions (CR-A and CR-B) and is tyrosine as well as serine/threonine phosphorylated during in vitro sperm capacitation. Thus far, the detailed information on CABYR protein expression in mouse spermatogenesis is lacking. Moreover, because of the complexity of this polymorphic ...
متن کاملTesticular FasL is expressed by sperm cells.
The testis is the main source of Fas ligand (FasL) mRNA in rodents; it is generally believed that this molecule, expressed on bordering somatic Sertoli cells, bestows an immune-privileged status in the testis by eliminating infiltrating inflammatory Fas-bearing leukocytes. Our results demonstrate that the attribution of testicular expression of FasL to Sertoli cells is erroneous and that FasL t...
متن کاملCABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath.
Calcium-binding tyrosine phosphorylation-regulated protein (CABYR) is a highly polymorphic calcium-binding tyrosine- and serine-/threonine-phosphorylated fibrous sheath (FS) protein involved in capacitation. A putative domain (amino acids 12-48) homologous to the regulatory subunit of type II cAMP-dependent protein kinase A (RII) dimerisation and A kinase-anchoring protein (AKAP)-binding domain...
متن کاملGene deletions in an infertile man with sperm fibrous sheath dysplasia.
BACKGROUND Asthenozoospermia may sometimes be related to genetic structural defects of the sperm tail detectable by transmission electron microscopy. Dysplasia of the fibrous sheath (DFS) is a genetic sperm defect, characterized by dysplastic development of the axonemal and periaxonemal cytoskeleton. We report the case of an infertile man with normal sperm count and total sperm immotility in wh...
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ژورنال
عنوان ژورنال: Journal of Translational Medicine
سال: 2009
ISSN: 1479-5876
DOI: 10.1186/1479-5876-7-61